Meaning: something or someone out of their comfort zone
Rewrite 1: like a bird out of the nest
Rewrite 2: like a cow out of the pasture
Rewrite 3: like a horse out of the barn
Rewrite 4: like a dude out of beer
Comment: The last one’s pushing the allusion, but I wanted to take you beyond the animal metaphor.
Check out the searchable alphabetical list of my cliché rewrites with the archive list at the right.